Safety and potential side-effects should always be an area of concern when adding a dietary supplement to your daily regimen. Used for centuries for food and medicinal purposes in its native West Africa, African mango has long been regarded as highly safe.
One of the most-studied diet supplements ever, African Mango (Irvingia gabonensis) has been the subject of over 30 scientific studies, examining various properties of the plant, its seed and its extract on humans and animals. All of these studies have indicated that it is a very safe substance. There was no acute toxicity noted either in human or animal studies.
You should not take irvingia gabonensis supplements if you have had an allergic reaction to any irvingia plant in the past. Also, be wary of African bush mango seeds from eastern Nigeria, as these have a history of being contaminated with aflatoxins and fungi.
In the study published in the journal of Lipids in Health and Disease, a minority of the subjects noted side effects including:
However the study goes on to note that these same side effects were also reported among subjects in the placebo group (the people who were not given the Irvingia supplement) and concludes that the formula "had few, if any, negative side effects."
There are no studies on drug interactions or safety in pregnant or nursing women - if you are pregnant or take other medications, play it safe and ask your doctor. For that matter, we urge you to always check with your doctor before starting any diet or adding a new supplement to your daily routine.